KETOPROFEN
 "N .S .A .I."

Composition:
    Suppositories    Capsules
Ketoprofen    100 mg/ supp    50 mg/ cap

Properties:
-    Ketoprofen has anti-inflammatory, anti-pyretic and analgesic activities.
-    Ketoprofen is more tolerance than aspirin and indomethacin.
-    Ketoprofen is an effective inhibitor of the cyclo-oxygenase enzyme which is responsible for the biosynthesis of prostaglandines.

Indications:
-    Rheumatoid arthritis.
-    Osteoarthrosis (osteoarthritis).
-    Trauma, post exercise pain.
-    Postoperative pain.
-    Lower back Pain.
-    Dysmenorrhea.
-    Soft tissue disorders.

Cautions: 
-    Ketoprofen affects platelate function, so it should not be given with oral anti-coagulants such as coumarin.
-    Ketoprofen should be used with caution in the elderly and in patients with a history of gastro-intestinal disorder.
-    Patients with hepatic or renal diseases should be observed while receiving Ketoprofen.

Side effects:
G I erosion, abdominal discomfort, anorexia and diarrhea.

Contraindications:
-    Sensitivity to Ketoprofen.
-    Sensitivity to Aspirin.
-    Bronchospasm (asthma).
-    History of active peptic ulcer.

Drug Interactions:
-    Anti-hyperglycemic: it in creases the effect of Ketoprofen. 
-    Anti-hypertensive: it reduces the effect of Ketoprofen.
Dosage and administration:
-    (1 – 2) suppositories daily or as directed by the physician.
-    One capsule (1 – 3) times daily after meals. 

Presentations:
-    Ketoprofen Capsules:    Box contains 20 capsules.
-    Ketoprofen Suppositories:    Box contains 10 suppositories.