التركيب :
كل مضغوطة ملبسة تحوي : 25 ملغ هيدروكسيزين هيدروكلورايد .
كل 5 مل تحوي على 10 ملغ هيدروكسيزين هيدروكلورايد .
الخواص الدوائية :
الاستطبابات :
مضادات الاستطباب :
الحمل والإرضاع :
الاحتياطات :
المركزية الأخرى مثل : المخدرات – المسكنات – الباربيتوريات.
التأثيرات الجانبية :
الآثار الجانبية المصاحبة للعلاج هيدروكسيزين هيدروكلورايد تكون عادة متوسطة الشدة وعابرة.
فرط الجرعة :
الجرعة و طريقة الاستعمال :
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الأطفال تحت 6 سنوات : 50 ملغ يومياً مقسمة إلى عدة جرعات . |
الأطفال فوق 6 سنوات : 50 – 100 ملغ يومياً مقسمة إلى عدة جرعات . |
الكبار : 50 – 100 ملغ أربع مرات يومياً . |
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الأطفال تحت 6 سنوات : 50 ملغ يومياً مقسمة إلى عدة جرعات . |
الأطفال فوق 6 سنوات : 50 – 100 ملغ يومياً مقسمة إلى عدة جرعات . الكبار 25 ملغ ثلاث أو أربع مرات يومياً . |
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يحفظ بدرجة حرارة دون 25 م°.
لا يصرف إلا بموجب وصفة طبية.
كل علبة تحتوي على 20 مضغوطة ملبسة .
كل زجاجة تحتوي على 10 مل شراب .
Composition:
Each coated tablet contains: Hydroxyzine HCl 25 mg.
Each 5 ml contains: Hydroxyzine HCl 10 mg.
Clinical Pharmacology:
- Atax Mediotic is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the central nervous system.
- Primary skeletal muscle relaxation, bronchodilator activity, antihistaminic, analgesic and antiemetic effects have been demonstrated experimentally and confirmed clinically.
- Clinical studies indicate that Hydroxyzine in therapeutic dosage does not increase gastric secretion nor acidity, and in most cases has mild antisecretory activity.
- Hydroxyzine is rapidly absorbed from the gastrointestinal tract and Atax Mediotic’s clinical effects are usually noted within 15 – 30 minutes after oral administration.
Indications:
- For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested.
- Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine–mediated pruritus.
- As a sedative when used as premedication and following general anesthesia.
Contra-Indications:
- Clinical data in human beings are inadequate to establish safety in early pregnancy. Until such data are available, Hydroxyzine is contraindicated in early pregnancy.
- Hydroxyzine is contraindicated for patients who have shown a previous hypersensitivity to it.
Warnings:
Nursing Mothers: It is not known whether this drug is excreted in human milk. Since many drugs are so excreted, this medication should not be given to nursing mothers.
Precautions:
- The potentiating action of Hydroxyzine must be considered when the drug is used in conjunction with central nervous system depressants such as narcotics, non-narcotic analgesics and barbiturates.
- Therefore when central nervous system depressants are administered concomitantly with Hydroxyzine their dosage should be reduced.
- Since drowsiness may occur with use of this drug, patients should be warned of this possibility and cautioned against driving a car or operating dangerous machinery while taking this medication.
- Patients should be advised against the simultaneous use of other CNS depressant drug, and cautioned that the effect of alcohol may be increased.
Adverse reactions:
Side effects reported with the administration of this medication are usually mild and transitory in nature
- The most common side effects: dry mouth and drowsiness.
- Respiratory depression, involuntary motor activity including tremor and convulsions have been reported, usually with doses considerably higher than those recommended.
Overdosage:
- The most common manifestation of this medication overdosage is hypersedation.
- If vomiting has not occurred spontaneously, it should be induced. Immediate gastric Iavage is
also recommended.
- General supportive care, including frequent monitoring of the vital signs
and close observation of the patient, is indicated.
Dosage & Adminstration:
- For symptomatic relief of anxiety and tension in:
Children under 6 years: 50 mg daily in divided doses.
Childern over 6 years: 50 – 100 mg in divided doses.
Adults: 50 - 100 mg (4 times daily).
- For use in the management of pruritus due to allergic conditions:
Children under 6 years: 50 mg in divided doses.
Children over 6 years: 50 – 100 mg daily in divided doses.
Adults: 25 mg (3 or 4 times daily).
- As a sedative when used as a premedication and following general anesthesia: 50 – 100 mg in adults, and 0.6 mg / kg in children.
- As with all medications, the dosage should be adjusted according to the patient’s response to therapy.
Storage:
- Store below 25 °C.
- Do not despense with out a medical prescription.
Presentation:
- Each box contains 20 cotated tablets.
- Each Bottle contains 100 ml syrup.